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The first prioirty that all clinicians think of once a patient is diagnosed with AF. When to start OAC and which one to choose, and when should we send the patient to LAA closure. 2024 ESC Guidelines for the management of Atrial Fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) https://www.escardio.org/Guidelines/C... 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Associationfor Cardio-Thoracic Surgery (EACTS) - Supplementary data https://academic.oup.com/eurheartj/ad... Efficacy and Safety of Novel Oral Anticoagulants in Patients With Atrial Fibrillation and Heart Failure: A Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/27614... RE-LY trial. Dabigatran versus Warfarin in Patients with Atrial Fibrillation https://www.nejm.org/doi/full/10.1056... ENGAGE AF-TIMI 48. Edoxaban versus Warfarin in Patients with Atrial Fibrillation https://www.nejm.org/doi/full/10.1056... ARISTOTLE trial. Apixaban versus Warfarin in Patients with Atrial Fibrillation https://www.nejm.org/doi/full/10.1056... ROCKET-AF trial. Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation https://www.nejm.org/doi/full/10.1056... Apixaban compared to heparin/vitamin K antagonist in patients with atrial fibrillation scheduled for cardioversion: the EMANATE trial https://pubmed.ncbi.nlm.nih.gov/29659... FRAIL-AF trial. Safety of Switching From a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients With Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial https://pubmed.ncbi.nlm.nih.gov/37634... ATRESIA trial. Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation https://www.nejm.org/doi/full/10.1056... ACTIVE-W trial. Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial https://pubmed.ncbi.nlm.nih.gov/16765... PRAGUE-17 trial. Left Atrial Appendage Closure Versus Direct Oral Anticoagulants in High-Risk Patients With Atrial Fibrillation https://pubmed.ncbi.nlm.nih.gov/32586... Pantoprazole to Prevent Gastroduodenal Events in Patients Receiving Rivaroxaban and/or Aspirin in a Randomized, Double-Blind, Placebo-Controlled Trial https://pubmed.ncbi.nlm.nih.gov/31054...