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Duramesh Lyo is biological a dural patch totally reabsorbable, made of an equine acellularized pericardium and it's processed to grant resistance, biocompatibility and easy handling. It's indicated for dural replacement or reinforcement in neuro and spinal procedures. Thanks to the manufacturing process developed and improved through years of experience, the membrane is easy to handle and fits defects even irregular anatomical structures. Despite the reduced thickness and the high transparency – important characteristics in several surgeries – Duramesh Lyo keeps a highly resistant structure and can be sutured without breaking. Duramesh Lyo has been successfully used in the surgery treatment of Arnold Chiari malformations and it's part of a specific protocol developed (after more than 1000 revised cases) by Neurologic Institute "Carlo Besta" (Milan, Italy).