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结肠癌预后效果如何 刘晓玲 山西省肿瘤医院 结肠癌的预后与患者的分期部位以及基因突变情况,都有关系,首先是结肠癌的分期,Ⅰ期到Ⅳ期的患者,预后情况是大不一样的,Ⅰ期,Ⅱ期的患者预后比较好,甚至可以治愈,Ⅲ期的患者,复发率增高,相应的治愈率下降,Ⅳ期理论上讲是不可治愈的但是可以通过,有效的治疗,延长生存期,提高生活质量,那么我国,临床就诊的结肠癌患者,多已进入中晚期,治疗效果不佳,由于结肠癌容易复发,一定要重视术后的复查,通常术后两年内,每三个月要做一次复查,第二是与部位有关系,早年认为左半结肠癌,和右半结肠癌,是同一种疾病的不同位置,但是近年来研究发现,右半结肠癌和左半结肠癌,是完全不同的两种疾病,解剖位置不同,基因突变不同,对治疗的反应也不一样,预后情况也不一样,美国癌症数据库,SEER数据库的资料表面,左半结肠癌平均生存时间,可以达到89个月,而右半结肠癌,平均生存期只有78个月,第三与患者,基因突变的情况有关,对于有BRAF基因突变,或者是有RAS基因,突变的患者,预后相对比较差。 What is the prognosis of colon cancer The prognosis of colon cancer, the staging site and gene mutation, It's all related, The first is the stage of colon cancer, Stage I to stage IV patients, The prognosis is very different, Phase I, The prognosis of stage II patients was better, It can even be cured, Stage III patients, The recurrence rate increased, The corresponding cure rate decreased, In theory, stage IV is incurable, but it can be passed, Effective treatment, Extended survival, Improve the quality of life, Then our country, Patients with colon cancer in clinical treatment, Most of them have entered the middle and late stage, The treatment effect is not good, Because colon cancer is easy to recur, We must pay attention to the reexamination after operation, Usually within two years after surgery, Every three months, we need to have a reexamination, Second, it is related to the position, In the early years, it was thought that the left colon cancer, And right colon cancer, It's different locations of the same disease, But in recent years, research has found that, Right and left colon cancer, It's two different diseases, The anatomical position is different, Gene mutations are different, The response to treatment is different, The prognosis is different, American cancer database, Data surface of SEER database, Mean survival time of left colon cancer, 89 months, And right colon cancer, The average survival time is only 78 months, Third, patients, The mutation is related, For those with BRAF mutations, Or there's a ras gene, Patients with mutations, The prognosis was relatively poor.