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Chronic cancer pain continues long after the injury or treatment is over, and can range from mild to severe. Chronic cancer pain is also called persistent pain and can be experienced at all times. The term refractory cancer pain is used when your pain cannot be controlled by medication anymore or you cannot take the medication due to the side effects. Description: Chronic cancer pain continues long after the injury or treatment is over, and can range from mild to severe. Chronic cancer pain is also called persistent pain and can be experienced at all times. The term refractory cancer pain is used when your pain cannot be controlled by medication anymore or you cannot take the medication due to the side effects. INTRATHECAL DRUG DELIVERY ALLOW PATIENTS TO GAIN CONTROL OVER THEIR CANCER PAIN OR TO DECREASE THE SIDE EFFECTS FROM ORAL PAIN MEDICATION¹,³ References 1. Bhatia G, Lau ME, Koury KM and Gulur P. Intrathecal Drug Delivery (ITDD) systems for cancer pain. F1000Research 2014, 2:96 (doi: 10.12688/f1000research. 2-96.v4) 2. Smith TJ, Staats PS, Deer T, Stearns LJ, et al. Randomized clinical trial of an implantable drug delivery (IDDS) system compared with comprehensive medical management (CMM) for refractory cancer pain: impact on pain, drug-related toxicity, and survival. J Clin Oncol. 2002;20(19):4040-4049. 3. Smith TJ, Coyne PJ. Implantable drug delivery systems (IDDS) after failure of comprehensive medical management (CMM) can palliate symptoms in the most refractory cancer pain patients. J Pall Med. 2005;8(4):736-742.