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NOTE: The recording of the session ends rather abruptly abruptly due to a technical difficulty during the original presentation. Apologies! Abstract: Psychedelics substances are increasingly investigated for their therapeutic effects. However, their clinical mechanisms of action remain poorly understood. In a series of studies, we have therefore investigated how classic psychedelics alter human brain function as well as emotional and social processing. We show that psychedelics alter information processing in the brain in a way that is distinct from non-pharmacologically induced altered states of consciousness (e.g., via meditation and hypnosis). Furthermore, we show that psychedelics change emotion processing and social behavior. These psychedelic-induced effects may contribute to clinical efficacy and have important implications for the therapeutic approach. Additionally, the results point to potential measures that could be used for the identification of patients who benefit most from psychedelic-assisted therapy. Speaker Bio Katrin Preller, PhD, PD, Group leader, University of Zurich, Boehringer-Ingelheim GmBH Katrin Preller received her M.Sc. (Neuropsychology and Clinical Psychology) from University of Konstanz, Germany. She joined the University of Zurich where she investigated the neurobiological long-term effects of cocaine, MDMA, and heroin use. After completing her PhD, she investigated the effects of psychedelics in mechanistic and clinical studies. She received a SNSF PostDoc mobility fellowship and worked at the Wellcome Trust Centre for Neuroimaging, UCL, London, and Yale University, New Haven. Subsequently, she was appointed as Group Leader at the University of Zurich and holds a position as Principal Clinical Biomarker Lead at Boehringer-Ingelheim.