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Mitochondria play an important role in cellular energy production, metabolic processes, and overall health. When they are not functioning well, the impact can extend to many chronic conditions. There can be multiple bottlenecks such as succinic acid, pyruvate and lactate ratios, and citrate levels. This presentation reviews: How mitochondrial dysfunction contributes to conditions such as fatigue, inflammation, and metabolic imbalances. Practical methods to measure mitochondrial performance in patients. Approaches to design targeted interventions based on specific dysfunctions. 00:01 Understanding Fatigue: Definitions and Symptoms 03:37 Exploring Mitochondrial Dysfunction 07:48 Conventional Lab Testing for Fatigue 11:27 Case Study: Analyzing Patient Symptoms 20:00 Theriome Aristotle Test: A Metabolomic Approach 23:49 Metabolite Analysis and Health Indicators 26:20 Digital Twinning and Personalized Protocols 28:13 Dietary Recommendations for Health Improvement 29:09 Gut Health and Neurocognitive Support 30:37 Detoxification Strategies and Environmental Exposures 32:51 Fatigue and Mitochondrial Dysfunction 36:50 Methylene Blue and Detoxification Protocols 40:02 Environmental Factors and Hormonal Influences 44:05 Light Therapy and Mitochondrial Function