Why gentamicin levels are taken - pharmacokinetics, dosing, monitoring, creatinine clearance скачать в хорошем качестве

Why gentamicin levels are taken - pharmacokinetics, dosing, monitoring, creatinine clearance

This video goes through the concept of taking gentamicin levels are why they are taken in order to adjust a patient's gentamicin dosing. Also include gentamicin pharmacokinetics, dosing, monitoring, and the Cockroft-Gault formula for creatinine clearance. (Sorry about the choppy audio!) Time stamps: 0:00 Introduction 1:18 Plasma concentration curve 1:46 First order kinetics 2:45 Post antibiotic effect (POE) 2:59 Once daily dosing vs multi-day dosing 4:16 Concentration dependent killing 4:58 Why once daily is preferred 5:45 Gentamicin in renal impairment 6:51 Initial dose 7:31 Ideal body weight vs actual body weight in obesity 8:24 Deciding on the interval - taking gentamicin levels 10:41 Renal function 11:38 Creatinine 12:27 Cockroft-Gault equation for creatinine clearance Hospital pharmacists should also refer to their hospital gentamicin dosing guidelines. Websites used in the video: IMPACT Body Weight Calculator: https://impact.chp.gov.hk/calculator_... National Kidney Foundation: https://www.kidney.org/atoz/content/gfr MDCalc CrCl calculator: https://www.mdcalc.com/creatinine-cle... IMPACT CrCl calculator: https://impact.chp.gov.hk/calculator_... I write online tutorials going through Hong Kong registration past papers for pharmacists at www.pharmacyexamquestions.com