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Protostome and Deuterostome Development: Many animals can be described as having one of two developmental modes: protostome development or deuterostome development. These modes can generally be distinguished by differences in cleavage, coelom formation, and fate of the blastopore. Cleavage: Many animals with protostome development undergo spiral and Determinate cleavage. The determinate cleavage of some animals with protostome development rigidly casts (“determines”) the developmental fate of each embryonic cell very early. In contrast to the spiral cleavage pattern, deuterostome development is predominantly characterized by radial cleavage. Most animals with deuterostome development also have indeterminate cleavage, meaning that each cell produced by early cleavage divisions retains the capacity to develop into a complete embryo. Coelom formation: Coelom formation begins in the gastrula stage. In protostome development, the coelom forms from splits in the mesoderm. In deuterostome development, the coelom forms from mesodermal outpocketings of the archenteron. Fate of the blastopore: In protostome development, the mouth forms from the blastopore. In deuterostome development, the mouth forms from a secondary opening. #Protostomes #Deuterostomes