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Analytical performance of TruSight™ Oncology 500 ctDNA v2

Presented By: Jennifer S. Lococo, PhD, Maria Jarama Ruiz, B.S., M.S. & Biswajit Das, Ph.D. Speaker Biography: Jennifer S. LoCoco, PhD is a Director of Assay Development at Illumina. She earned her Bachelor of Sciences degree in Biology from the University of Utah and a PhD in Molecular Biology at The University of California, San Diego. Following postdoctoral work on transcriptional control of ciliogenesis at the Salk Institute for Biological Sciences she started her career in assay development with a focus on genetic testing. She and her team currently work to design and optimize library preparation methods to enrich for oncology relevant variants in various biopsy types (FFPE, cfDNA) for further interrogation using next generation sequencing. Maria embarked on her professional journey in the research space, delving into the intricate field of pharmacogenetics, where she spent a significant portion of her career. Driven by a thirst for new challenges and opportunities, she transitioned into the dynamic realms of commercialization and marketing. Her venture into product management commenced at CTK Biotech, a pivotal juncture that marked the beginning of her leadership journey. At CTK Biotech, Maria assumed responsibility for steering the company's molecular diagnostic portfolio, showcasing her prowess in strategic leadership and innovation. Her tenure at CTK Biotech provided her with invaluable experience in navigating the complexities of product development and commercialization within the biotechnology landscape. In 2022, Maria embarked on a new chapter in her career by joining Illumina's Reproductive Health Product Management team. Here, she capitalized on her expertise to spearhead product strategy and market development initiatives, playing a pivotal role in advancing Illumina's portfolio in reproductive health. Driven by her unwavering passion for making a tangible impact in healthcare, Maria transitioned to Illumina's oncology business unit two years ago. In her current role, she continues to leverage her extensive experience in product management to drive innovation and deliver cutting-edge solutions in the field of oncology diagnostics. Maria's professional journey is characterized by her relentless pursuit of excellence and her ability to thrive in diverse and challenging environments. With a keen eye for innovation and a passion for driving positive change, she remains poised to make meaningful contributions to the future of healthcare Dr. Biswajit Das serves as the Senior Principal Scientist in Molecular Characterization Laboratory at Frederick National Laboratory for Cancer Research. With more than a decade of experience, he specializes in developing genomic assays to identify predictive biomarkers. Over the past eight years, his research has also focused on utilizing ctDNA biomarkers in clinical trials. His team collaborates on genomic biomarker studies for several clinical trials sponsored by the NCI. Dr. Das earned his PhD from Jadavpur University in Kolkata, India, and completed his postdoctoral research at the Carnegie Institution in Baltimore, Maryland. Webinar: Analytical performance of TruSight™ Oncology 500 ctDNA v2 Webinar Abstract: Next-generation sequencing (NGS) based liquid biopsy is emerging as standard of care in oncology for comprehensive genomic profiling (CGP) of solid tumors. In this presentation we will showcase the analytical performance of TruSight™ Oncology 500 ctDNA version 2 (TSO 500 ctDNA v2, Illumina, San Diego, CA; Research Use Only), an NGS-based assay that utilizes the same gene panel as TSO 500 ctDNA. Its improved workflow reduces cfDNA input requirements, total turn-around time and hands-on time while still delivering all key biomarker data available from the TSO 500 gene panel. Learning Objectives Understand enhancements and features of TSO 500 ctDNA v2 Comprehensive overview of analytical performance Introduce performance data from an early access customer Labroots on Social: Facebook:   / labrootsinc   Twitter:   / labroots   LinkedIn:   / labroots   Instagram:   / labrootsinc   Pinterest:   / labroots   SnapChat: labroots_inc

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