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Generalised epilepsy is often described as involving the whole brain at once. But does it start all at once? Dr. Frederic Schaper discusses research mapping subtle brain abnormalities to shared brain networks in generalised epilepsy, and how these networks overlap with targets used for deep brain stimulation. The conversation explores what this may reveal about seizure mechanisms and future neuromodulation research. This episode is sponsored by EASEE® by Precisis GmbH and had no influence over the editorial content or discussion. Learn more about EASEE® here: https://precisis.de/en 📖 Chapters 00:00 Trailer & intro 01:29 Generalised epilepsy: what does it mean? 02:57 Mapping epilepsy and psychiatric symptoms to brain networks 04:33 Neurodegeneration and generalised epilepsy 05:37 Deep Brain Stimulation (DBS) identifying abnormal activity 07:00 Subtle brain changes that reveal seizure patterns 08:44 A shared network across seizure types 10:08 Future research on generalised epilepsy and DBS 11:34 Where neuromodulation fits in treatment 13:09 Neuropsychiatric symptoms of epilepsy 15:34 Thank you to patients contributing to research 16:10 Closing thoughts & thanks 🔗 More about episode (inc. transcription) 👇🏻 https://www.epilepsysparks.com/epilep... 🌐 More about Frederic 👇🏻 https://www.epilepsysparks.com/guests... 📃 Paper "A generalized epilepsy network derived from brain abnormalities and deep brain stimulation" 👇🏻 https://www.nature.com/articles/s4146... 👕 Join the Epilepsy Sparks community with our merch 👇🏻 https://epilepsy-sparks.creator-sprin... 🌐 More Epilepsy Sparks Insights 👇🏻 https://www.epilepsysparks.com/epilep... 🎧 Listen to the Epilepsy Sparks Insights podcast on Apple, Spotify, or your favourite provider! 🔤 Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary 📲 Join us on social media! LinkedIn / epilepsy-sparks Instagram / epilepsysparks Facebook / epilepsysparks TikTok / epilepsysparks Bluesky https://bsky.app/profile/epilepsyspar... #generalisedepilepsy #deepbrainstimulation #brainnetworks #neurology #neuroscience #epilepsyresearch #epilepsysparks @EASEE.epilepsie @harvardmedicalschool @brighamwomenshospital