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New research published on bmj.com looks at effectiveness of a wound-edge protection device to prevent surgical site infections. Surgical site infection is one of the most common postoperative complications, occurring in at least 5% of all patients undergoing surgery and 30-40% of patients undergoing abdominal surgery, depending on the level of contamination. As most infections are the result of wound contamination by endogenous bacteria from the patient's skin, mucous membranes, or hollow viscera, the concept of using a physical barrier to cover the cut edges of the wound has been revisited by surgeons many times over the past half century. This protection can take the form of a wound edge protection device or "wound guard" that is inserted into the wound for the duration of the operation. The authors assessed the clinical effectiveness of wound edge protection devices in reducing rates of infection at the site of surgery in patients undergoing open abdominal surgery to evaluate the impact on patients' health related quality of life and length of hospital stay. Read the open access article online: http://www.bmj.com/content/347/bmj.f4305