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How do tumor mutations like ESR1 or PIK3CA affect your treatment options? In this video, Dr. Jennifer Griggs explains the crucial difference between inherited and tumor gene mutations in breast cancer. You'll learn how mutations like BRCA1, BRCA2, CHEK2, ATM, TP53, ESR1, MAP3K1, and PIK3CA can influence your cancer risk, treatment resistance, and eligibility for targeted therapies. She discusses which mutations can be passed down through your family and which ones develop over time inside tumor cells—especially after treatment. If you’ve ever been confused about what mutations actually means for your care, this video breaks it down clearly. ⭐️ Get your personalized Yerbba Report at https://www.yerbba.com/ Use code YOUTUBE15 when you sign-up. Connect With Yerbba! INSTAGRAM: / yerbba FACEBOOK: / yerbba.breast.cancer BLOG: https://www.yerbba.com/blog Chapters 0:00 Introduction 0:53 Inherited Mutations 2:02 CHEK2, BRIP1 ATM, and RAD51C and RAD51D. 3:04 Tumor Mutations 4:03 ESR1 Mutations 4:41 MAP3K1 Mutations 5:04 TP53 Mutations 5:43 PIK3CA Mutations 6:31 What Causes Mutations? #breastcancer #breastcancertreatment #brca1 #brca2 #tumortreatment #mutation #genetictesting #breastcancersupport #breastcancerthriver Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental health professional, or other qualified health provider with any questions you may have regarding your medical condition.