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Dr. James Lewerenz notes that if you consume cannabis with bacterial contaminants such as E-Coli or Salmonella, it presents itself as a negative foreign substance in your body and triggers an immune response. If cannabis contains dangerous levels of mold or yeast, consumption could cause an autoimmune disorder that could manifest itself in the brain, heart, lungs, or entire body. These result in symptoms of infection and can also negatively affect brain function. Untested cannabis can also be contaminated with dangerous levels of pesticides. Dr. Lewerenz points out that for some this could trigger autoimmune or hypersensitivity responses. Untested cannabis may also contain heavy metals which are extremely neurologically toxic and can affect crucial functions like memory and balance, as well as cause allergic reactions and long-term lung damage.