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Varicose disease is a three-dimensional pathology and must be treated by means of a three-dimensional method: TRAP (Three-dimensional Regenerative Ambulatory Phlebotherapy). TRAP reduces hemodynamic hypertension in the venous circulation and corrects excessive hydrostatic thrust. A regenerative solution is injected into all the visible veins. When the solution comes into contact with the vessel walls, it narrows and strengthens the vessels. Traditional techniques have no pathophysiological basis. Stripping out the veins, burning them with a laser or obliterating them with sclerotherapy not only eliminates the escape valve of hemodynamic hypertension, it also eliminates the “gateways” through which the walls of the non-visible veins can be treated. In addition, as Doppler study cannot visualize the pathology, patients with multiple incontinent perforating veins are regarded as having no dysfunction. In the lower limbs, however, even the smallest telangiectasia is caused by hemodynamic hypertension.