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Today’s AI news is dominated by a clear inflection point: agentic AI is moving from raw capability to trusted, enterprise- and security-grade deployment. The most impactful development comes from OpenAI, which introduced GPT-5.3-Codex alongside Trusted Access for Cyber—an identity- and trust-based framework that gates powerful cyber capabilities behind verified access, auditability, and safeguards. This is a signal moment: frontier models are no longer just “smarter,” they are being explicitly designed for regulated, high-risk domains. In parallel, OpenAI showed tangible economic impact, with GPT-5 cutting cell-free protein synthesis costs by 40% in an autonomous lab setup—reinforcing that agentic AI is now delivering measurable productivity gains in science and biotech. Reasoning and verification remain a central tension. Wired highlighted a new AI math startup solving previously unsolved problems, underscoring rapid advances in formal reasoning. Yet arXiv papers documenting fabricated citations at NeurIPS 2025 expose a systemic failure mode in AI-assisted research and peer review. The takeaway is stark: capability is racing ahead of institutional controls, making trust, provenance, and validation non-negotiable. Enterprises are responding by stress-testing agents before scaling them. Fortune reports how United Rentals deliberately tried to break its own AI agent before rolling it out to thousands of employees—a best practice more companies will need to adopt. On the platform side, AWS continues to push generative AI deeper into core business workflows, while new tools across Product Hunt focus on agent identity, secrets management, and governance—critical infrastructure for the “AI coworkers” era. Bottom line: The AI conversation is shifting decisively from what models can do to who should be allowed to use them, under what conditions, and with what guarantees. GPT-5.3-Codex + Trusted Access is not just a model release—it’s a blueprint for how frontier AI enters the real world. #ArtificialIntelligence #AgenticAI #AIInfrastructure #CyberSecurity #TrustedAI #EnterpriseAI #OpenAI #FoundationModels #FutureOfWork / issue-103-sam-ghosh-afesc https://asthalavista.com/