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Keynote by Murat Kuscu recorded at the 6th Workshop on Molecular Communications (MolCom), July 13th-15th, 2022. Workshop was held at the University of Warwick, Coventry, UK. MolCom Workshop Playlist: • 6TH WORKSHOP ON MOLECULAR COMMUNICATIONS J... Workshop website: https://molecularcommunications.org/ Keynote Summary: Molecular Communications (MC) is promising as a common communication modality among artificial micro/nanoscale devices and natural/synthetic biological entities. Although much has been done theoretically for exploring the promises and limitations of MC, the lack of experimental validations has led to a significant gap between theory and practice in many aspects. This issue has so far impeded the development of practical MC applications, and thus, been calling for more experimental research driven by truly interdisciplinary approaches. This talk will first provide a brief overview of recently proposed nanomaterial-based and synthetic biology-based practical MC transceiver architectures with an emphasis on our own attempt at fabricating micro/nanoscale MC receivers and microfluidic MC testbeds based on graphene and related nanomaterials. This overview will lead to a more extensive discussion on physically relevant challenges revealed by the recent MC experiments, such as those regarding the interference and noise in physiological environments, modelling, and optimisation in the face of nonlinearities, as well as the opportunities stemming from peculiar interactions at the bio-electronic interfaces. A particular focus will be paid to the promises of engineering ligand-receptor interactions for tackling the adaptivity, multi-access, co-existence and limited data-rate challenges of molecular communication networks. Presenter Bio: Murat Kuscu is an Assistant Professor and an MSCA Fellow at the Department of Electrical and Electronics Engineering, Koç University, Turkey, where he is also acting as the Director of Nano/Bio/Physical Information and Communications Laboratory, and the Associate Director of the Nanofabrication and Nanocharacterization Center (n2STAR). He received his PhD degrees in engineering from University of Cambridge, and in electrical and electronics engineering from Koç University. His current research interests include molecular communications, nanoscale biosensors, microfluidics, and Internet of Bio-Nano Things. He has received the University of Cambridge CAPE Acorn Post-graduate Research Award 2019, IEEE Turkey Ph.D. Thesis Award 2018, and Koç University Academic Excellence Award 2018 with his theoretical and experimental research on molecular communications.