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On March 13, 2026, the American College of Cardiology (ACC) and American Heart Association (AHA) released an updated clinical guideline for the management of dyslipidemia, replacing the 2018 Guideline on the Management of Blood Cholesterol. Among the most major changes in these guidelines is the shift from percent reduction of LDL-C back to specific, targeted goals. The 2018 version encouraged the use of percent LDL-C reductions as a method of monitoring lipid levels and guiding lipid-lowering therapy (LLT) across the board. Additionally, secondary prevention now includes LDL-C goals as well, with recommendations shifting for LDL-C ≥190 mg/dL and familial hypercholesterolemia (FH). “I love coming back to goals,” Viet Le, DMSc, PA-C, told HCPLive in an exclusive interview. “It was a little nebulous to just throw out percent reduction of LDL cholesterol, so I think it’s helpful for patients and for clinicians alike to be able to see goals of where we’re going.” Read the full article here: https://www.hcplive.com/view/aha-acc-... #cardiology #dyslipidemia #cholesterol