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Gennaro D’Anna, MD, ASST Ovest Milanese, Legnano, Italy, discusses the challenges associated with diagnosing vascular cognitive impairment (VCI) using different imaging techniques. Dr D’Anna highlights the issue of variability in imaging techniques and interpretations among neurology professionals, emphasizing the urgent need for standardized protocols to ensure objective assessment of patients. Challenges such as limited sensitivity to early vascular changes and accessibility to advanced imaging techniques are also discussed. The conversation underscores the importance of collaborative efforts to overcome these challenges, especially considering the growing elderly population susceptible to VCI. This interview took place at the European Academy of Neurology (EAN) 2023 Congress in Budapest, Hungary. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.