NSS 2022.12.02 - Sangkyu Lee "Predicting and understanding normal tissue complication" скачать в хорошем качестве

NSS 2022.12.02 - Sangkyu Lee "Predicting and understanding normal tissue complication"

MPU Noon Seminar Series Speaker: Sangkyu Lee, Ph.D., DABR Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York Title: "Radiogenomics: Predicting and understanding normal tissue complication with genomics and machine learning” Abstract: The risk of normal tissue complications is one of the most important considerations in radiotherapy treatment planning. It has been observed that normal tissue response to the same dose level is heterogeneous among cancer patients. Radiogenomics is a study that searches for heritable genomic variations - coded by single nucleotide polymorphism (SNP) - that correlate with the heterogeneity in normal tissue response. Machine learning helps unveil the true correlates from high-dimensional genomic data. This talk will summarize the current status of Radiogenomics, and the works conducted by my research group at Memorial Sloan Kettering Cancer Center. Biographical Summary: Sangkyu (Kyu) Lee did both of his masters (supervisor: Dr. Jan Seuntjens) and PhD (supervisor: Dr. Issam El Naqa) in McGill MPU. His PhD work was on prediction of radiation pneumonitis by integrating biomarkers and dosimetry data. He left Montreal to join Memorial Sloan Kettering in NYC for 4-year medical physics residency program which included research fellowship under Dr. Joe Deasy. After his graduation, he continues to work for MSK as a clinical physicist.