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The extracellular landscape is more complex than we thought. Two recently identified nanoparticles, exomeres and supermeres, are entering the limelight in the extracellular particle field. In this video, Millie Johnston discusses how these tiny particles differ from extracellular vesicles (EVs), their potential roles in intercellular communication and some of the challenges that come with studying them. Whether you're focused solely on isolating EVs, or intrigued by the newcomers to the field, this video has useful information and tips for your research. 🕙 Time stamps: 00:00. Introduction 00:28. Exomere classification 00:50. Differences between exomeres and extracellular vesicles 1:22. Introduction to supermeres 2:05. Internalisation and function of supermeres 2:40. Isolating exomeres and supermeres 3:31. Measuring exomeres and supermeres Further resources: 🟣 The Non-Vesicular Wave: Exomeres, Supermeres and Beyond: https://www.izon.com/news/the-non-ves... 🟣 Dive into nanoparticle separation and the qEV Isolation platform: https://www.izon.com/qev/overview 🟣 Learn more about qEV isolation with the 20 nm column series: https://www.izon.com/qev/qev-series-c... 🟣 Keen to get in touch? Head to https://www.izon.com/contact