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🎯Master class of ICU series #21st 🩺 Antiviral drugs made easy 🏥🩺 @Life_in_ICU_yt 👈 follow Antiviral Drugs – Pharmacological Overview 1️⃣ Definition Antiviral drugs are medications used to treat viral infections by inhibiting viral replication or preventing the virus from entering host cells. 2️⃣ Common Viral Infections Treated Influenza HIV Hepatitis viruses (HBV, HCV) Herpes viruses (HSV, VZV) 3️⃣ Target in Viral Life Cycle Antiviral drugs act on specific stages of the viral life cycle, such as: Viral entry into host cell Uncoating of virus Replication of viral genetic material Protein synthesis Assembly and release of new viruses 4️⃣ Major Classes of Antiviral Drugs A. Reverse Transcriptase Inhibitors Used mainly for HIV treatment Block reverse transcriptase enzyme Prevent viral RNA from converting into DNA B. Protease Inhibitors Used in HIV therapy Inhibit viral protease enzyme Prevent formation of mature infectious virus particles C. Neuraminidase Inhibitors Used for Influenza virus Block neuraminidase enzyme Prevent release of new viruses from infected cells 5️⃣ Other Important Types Direct-Acting Antivirals (DAAs) – directly inhibit viral proteins (e.g., in hepatitis C). Nucleoside/Nucleotide Analogues – mimic nucleotides and stop viral DNA/RNA synthesis. Interferons – immune-modulating agents that enhance the body’s antiviral response.