Homology modeling using Modeller - Complete Tutorial for beginners (Part 1) скачать в хорошем качестве

Homology modeling using Modeller - Complete Tutorial for beginners (Part 1)

#Structure #Modeling #Proteins structure prediction #Tutorials #Easy #Guide #Proteomics 1 Go to the website of MODELLER https://salilab.org/modeller/ 2 Firstly, You need to get a license by using official email to download a software 3 Go to the registration page and get a license key using this link https://salilab.org/modeller/registra... 4 Prerequired for running a Modeller is #Python https://www.python.org/downloads/rele... 5 Modeller is a python based software for modelling the proteins. 6 Go to NCBI ,search for the desired protein and download its FASTA file. 7 After downloading , go to the documentation of Modeller software and save the file according to the format. 8 Remove the header line, add steric at the end of the sequence and save the file with .ALI extension. 9 While using BLAST, you can also find out the best possible hits for your query sequence. 10 Choose the first 4 on the basis of high percentage identity. 11 Go to RCSB PDB and download the template PDB files by their accession number in order to select template for our query structure. 12 Now save all the files in the Modeller directory.