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Tags: Delta-8 THC, Delta-8 Tetrahydrocannabinol, Cannabis History, Cannabis Research, Animal Studies, Medicine Michael Tagen, PhD presents "The Pharmacology of Delta-8-Tetrahydrocannabinol: A Review of 80 years of Studies" at CannMed 23. 0:00 Intro 0:20 Disclosures 0:34 Interest in Delta-8 THC 2:09 What is Delta-8 THC? 3:16 Cannabis Compound History 6:11 First Delta-8 THC Clinical Tests 8:05 Animal Studies 10:40 First Controlled Clinical Studies 12:20 Discovery of CB1 Receptor 13:13 Delta-8 THC Binding and Activation of the CB1 Receptor 15:28 Different Effects of Delta-8 THC & Delta-9 THC 16:52 Delta-8 THC effects at the CB2 Receptor 19:30 Conclusion 19:50 Q&A The objective of this analysis was to comprehensively review the scientific literature on the pharmacology of delta-8-THC (Δ8-THC) and how it compared to Δ9-THC. PubMed was searched for all publications related to in vitro binding and functional assays, in vivo assays, and clinical studies of Δ8-THC. Understand how the pharmacokinetics and pharmacodynamics (PK/PD) of delta-8-THC are similar and different to the PK/PD of delta-9-THC. Identify what we still do not know about the pharmacology of delta-8-THC and how we can fill these gaps with new studies. Learn More about CannMed: https://cannmedevents.com/