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What is SPECT?

SPECT stands for single photon emission computed tomography. A radioactive tracer like technetium sestamibi is injected intravenously and nuclear scan images using a gamma camera obtained after 20 minutes. This will show the uptake of the tracer at various regions of the heart. After that those who can walk on a treadmill will be connected with electrodes for monitoring ECG during the test. Treadmill slope and speed are typically increased every three minutes and maximal exercise without angina or ECG changes is achieved. The test is terminated earlier in case of significant angina, other major symptoms, or ECG changes. The ECG printouts are analysed by the supervising physician. At maximal exercise, one more injection of radioactive tracer is given. One more nuclear scan is done after waiting about 20 minutes with the gamma camera. The rest images are compared with the exercise images by the nuclear medicine physician.