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David Reich discusses the revolution wrought by the creation, 15 years ago, of a new tool for studying the human past: ancient DNA sequencing. The invention of the microscope around 400 years ago made possible the discovery of the world of previously invisible microorganisms. In the same way, when we obtain DNA from past cultures today, we find surprise after surprise, often in tension with what we thought we knew, based on archaeology, linguistics, and history. Reich explores how these new discoveries help us better appreciate our shared, and complicated, genetic past and how they might be used to improve human health today. Speaker David Reich, professor of genetics, Harvard Medical School; professor of human evolutionary biology, Harvard Faculty of Arts and Sciences; Howard Hughes Medical Institute Investigator Discussant Carl Zimmer, New York Times science columnist; author of Air-Borne: The Hidden History of the Life We Breathe (Dutton, 2025) and other books about science; professor (adjunct) of molecular biophysics and biochemistry and lecturer in English, Yale University For information about Harvard Radcliffe Institute and its many public programs, visit https://www.radcliffe.harvard.edu. Facebook: / radcliffeinstitute Bluesky: https://bsky.app/profile/rad-institut... Instagram: / radcliffe.institute LinkedIn: / radcliffe-institute