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Topic: Pathogens Why do we get fever? So that we can take a holiday from work. No. Fever is a protective response of our body to fight against pathogens such as bacteria, viruses and fungi. These pathogens cause diseases. Hence, when pathogens enter our body, the immune cells such as white blood cells produce chemicals called pyrogens which are released into the bloodstream. I thought like movies, they are released in theatres. Please, pay attention. Hypothalamus, which is a small part of our brain, regulates our body temperature. However, when these pyrogens reach the hypothalamus, it starts to raise our body temperature, thus producing fever. Now, one of the reasons for producing this fever is that many pathogens cannot survive at high temperatures. Thus, they die and we remain safe.