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From an observable phenotype, a new condition was described by John Langdon Down in 1866 who made the first diagnosis. His nomenclature 'Mongoloid' is antiquated and now avoided. Now it's classified in DSM-IV as a cognitive disorder. Get down, get down Hooked on spastics they follow us around. Get down, get down Corky didn't mean to set the restaurant on fire. Despite a disparate collection of symptoms, the underlying cause is a genetic syndrome. Where DNA is replicated, in an extra chromosome situated at the twenty-first pair out of twenty-three a process known as 'trisomy'. One in a thousand, say the statistics, have these typical characteristics. Get down, get down Hooked on spastics they follow us around. Get down, get down Hooked on spastics, I have an obsession with genetic over-expression. Life goes on... and on it goes We're dedicated to our favourite show! Get down, get down I'm a fan of the chromosomally endowed. Two's company, three's a crowd!