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Summary: Oral graft-versus-host-disease (GVHD) can cause numerous problems in the oral cavity after transplant.. This presentation describes various forms of oral GVHD and identifies remedies that can help patients manage the symptoms. Presenter: Katharine Ciarrocca DMD, MSEd Duke University Hospital https://www.dukehealth.org/find-docto... As presented at the 2025 Survivorship Symposium, May 3-9. Many thanks to Incyte whose support helped make this presentation possible. Presentation is 32 minutes long with 24 minutes of Q & A. To read the transcript, go to: Presentation is 32 minutes long with 24 minutes of Q & A. Highlights: (02:26): Oral Medicine is a specialty of dentistry that integrates medicine and dentistry to diagnosis and treat complex orofacial diseases, as well as oral complications of systemic disease. (03:08): The orofacial complex includes the teeth, t mucosa or the soft tissue lining of your mouth, salivary glands, gums, the bone that help hold the teeth in, and the temporomandibular joint and chewing system. (06:32): The symptoms of oral GVHD include pain, which is obviously a problem, and sensitivity to normally tolerated foods. It can also affect mouth opening and it can cause dry mouth. (07:20): Common forms of oral GVHD are reticular and ulcerative GVHD which can occur individually or together. (10:30): Oral GVHD can affect the salivary glands or the spit glands and cause dry mouth. (16:35): Saliva provides many protective functions as well as food and speech-related functions. (20:17): There are several steps patients can take to manage dry mouth. (24:44): Regular dental visits and meticulous oral hygiene can also help with dry mouth. (25:33): Oral chronic GVHD is a risk factor for oral cancer. (28:35): Oral GVHD should be assessed by a specialist who is familiar with this condition and the risk of developing oral cancer. Key Points: Oral graft-versus-host disease is usually chronic in nature and is caused by transplanted donor cells that mount an immune attack against the patient. There are several treatment options for oral GVHD including gels, rinses, ointments, and steroids. Patients with oral GVHD are encouraged to actively seek treatment to minimize symptoms and future risks. Oral chronic GVHD is a risk factor for oral cancer so patients should undergo screening at least once a year. They should also do self-exams and avoid things that cause oral GVHD to flare up. VISIT US ON SOCIAL MEDIA: / bmtinfonet / bonemarrowstemcelltransplantclub / bmtinfonet https://x.com/BMTInfoNet / bmt-infonet https://bsky.app/profile/bmtinfonet.b...