ArthroFlex® SCR Interview with Dr. O'Connell скачать в хорошем качестве

ArthroFlex® SCR Interview with Dr. O'Connell

Superior Capsular Reconstruction (SCR) involves the reconstruction of the superior capsule using ArthroFlex to provide a supplemental soft tissue covering to the glenohumeral joint which keeps the humeral head centered on the glenoid, thereby restoring normal joint biomechanics and stability. ArthroFlex is the only truly “decellularized” acellular dermal matrix (ADM) for use in Superior Capsular Reconstruction. Although several dermal products claim to be “decellularized”, not all decellularization processes meet the definition developed by Crapo, Gilbert and Badylak.* After evaluating remodeling responses and adverse cell and host responses, the authors determined that an ADM needs to meet certain criteria to satisfy the intent of decellularization. Inadequate decellularization leaves DNA and residual cellular material in allografts that can elicit adverse host reactions and negate constructive tissue remodeling. “Our data showed SCR with dermal allograft effectively restored the superior restraints in the glenohumeral joint and yielded outstanding clinical outcomes even after 2 years, making it an excellent viable alternative to RTSA.”** (Hirahara et al, 2017) *Crapo PM, Gilbert TW & Badylak SF. An overview of tissue and whole organ decellularization processes. Biomaterials. 2011. April;32(12):3233-3243. **Hirahara AM, Anderson WJ & Panero AJ. Superior Capsular Reconstruction: Clinical Outcomes After Minimum 2-Year Follow-Up. AJO. 2017 Nov/Dec: 46(6):266-272,278.