Altogen Biosystems In Vitro HUVEC Transfection Tutorial скачать в хорошем качестве

Altogen Biosystems In Vitro HUVEC Transfection Tutorial

Angiogenesis, or new blood vessel growth, is controlled by intercellular chemical signaling that can stimulate both the new vessel formation and damaged vessel repair. Angiogenesis deregulation is associated with various diseases, such as diabetic ulcers, cancer and cardiovascular disease, among others. Angiogenesis inhibitors are a well-used class of drugs that interfere with blood vessel formation which can, in some cases, be used to treat the aforementioned diseases. The Human Umbilical Vein Endothelial Cell line (HUVEC) is a powerful model that has been used to investigate physiological processes such as angiogenesis. The HUVEC line, aptly named, was established from human umbilical vein endothelial cells, and has been used to study the umbilical cord interior. It has been suggested that HUVECs may affect angiogenesis, which has implications in supporting cancer growth due to nutrient supply. Endothelial cells in general have key roles in many physiological and pathophysiological processes such as cancer development and arterial disease. HUVEC model systems have been commonly used for physiological investigations into processes such as macromolecule transport, fibrinolysis, and blood coagulation. HUVECs are shown to respond to cytokine stimulation. Altogen Biosystems provides a HUVEC-specific advanced formulation of a lipid-based transfection reagent kit for umbilical vein endothelial cells. https://altogen.com/product/huvec-tra...