(64) DNA Structure & Function | Deoxyribonucleic acid Structure & Function | Nucleic acid Metabolism скачать в хорошем качестве

(64) DNA Structure & Function | Deoxyribonucleic acid Structure & Function | Nucleic acid Metabolism

Download the "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Tests and other GPAT Materials - https://play.google.com/store/apps/de... Deoxyribonucleic acid (DNA) serves as the hereditary material, carrying the genetic instructions/information that are passed from parents to their offspring across generations, determining traits and functions of the organism. Stored as a code of chemical bases (A, T, C, G) in a double-helix structure Two types of Nucleic acids 1. Deoxyribonucleic Acid (DNA): DNA is organized into genes, the fundamental units of genetic information. 2. Ribonucleic Acid (RNA) DNA is composed of: 1. Nitrogenous bases a. Purines: Adenine (A), Guanine (G) b. Pyrimidines: Cytosine (C), Thymine (T) 2. Pentose sugar – Deoxyribose 3. Phosphate group Structure of DNA: Watson–Crick Model of DNA (B-DNA) Discovery • Proposed in 1953 by James Watson and Francis Crick • Watson and Crick proposed DNA double helix structure (B-DNA) with two polydeoxyribonucleotide chain (strand) chains. • The two strands are antiparallel: a. One strand runs 5′ → 3′ b. Other strand runs 3′ → 5′ • DNA is a polymer of deoxyribonucleotide with millions of nucleotides units joined by 3′–5′ phosphodiester bonds. • The two chains are complementary to each other, purine of one chain pairs with pyrimidine of the other. • Phosphodiester linkages form the sugar-phosphate backbone of DNA. • Diameter of double helix is 20 Ao (2 nm). • Distance between two adjacent base pairs is about 3.4 Ao (0.34 nm). • One complete turn is 34 Ao (3.4 nm) with 10 pairs of nucleotides per turn. • Bases are held together by hydrogen bonds: a. A–T: 2 hydrogen bonds b. G–C: 3 hydrogen bonds Base pairing follows Chargaff’s rule: Get in touch with the solution by just clicking the following links- Facebook Group-   / solutionpharamcy   Mobile App - https://play.google.com/store/apps/de... New Medicine Review Channel (Pharmacy Dictionary)    / @pharmacydictionary   E-Mail for official and other work - solutionpharmacy@gmail.com #solutionpharmacy #Pharmacologyclass #Pharmacology @solutionpharmacy