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Alcohol Withdrawal Symptoms, Timeline & Treatment Explained | Detox Guide | MedHeads In this compelling episode of Cracking Addiction, Dr. Ferghal teams up again with Dr. Richard to unpack the critical nuances of alcohol withdrawal, from its onset and symptom progression to clinical complications and evidence-based treatments. Together, they explore how understanding the natural history of alcohol detoxification can significantly improve outcomes for both patients and clinicians. Key Topics Covered: 1. Timing of Alcohol Withdrawal Symptoms Discover how symptoms can begin as early as 12–24 hours after the last drink, with detailed insights into the significant physiological changes occurring during the notorious ‘day two’ of withdrawal. 2. Complications and Risk Factors The episode dives deep into severe withdrawal complications, including seizures and delirium tremens (DTs). Learn how prior withdrawal history and comorbid conditions significantly elevate risk and influence clinical decisions. 3. Individualised Treatment Over Protocol-Driven Care Dr. Richard critiques the limitations of rigid detox protocols, advocating for personalised treatment strategies based on patient history and symptom severity. The role of benzodiazepines (especially diazepam) is discussed, with special attention to avoiding 'kindling' and other long-term risks. 4. Managing Seizures and DTs Practical guidance is shared on how to safely and effectively manage serious symptoms like seizures and DTs, including medication strategies and what not to use during acute withdrawal phases. Learning Outcomes: Recognize the early signs of alcohol withdrawal and their typical timeline. Understand the risks of protocol rigidity and the value of adaptive, patient-centered care. Learn evidence-based approaches to seizure prevention and DT management. Appreciate the importance of addressing the psychosocial dimensions of withdrawal alongside physical symptoms. This episode is a must-listen for healthcare professionals, medical students, and anyone interested in the science of addiction medicine. Whether you're managing alcohol withdrawal in clinical practice or seeking to understand its challenges more deeply, this conversation offers actionable insights rooted in real-world experience.