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Hello everyone welcome to Monu tutorial academy. today our topic is Rabies so first we will discuss about what is Rabies viruse and then we also study definition in easy way so you watch full video at till end. and learn everything in this Rabies video if you any doubt in this video so you ask me in comment box then I replied in shortly time. your doubt in any subject like hematology, microbiology then you tell me in comment box also. I will make also the hematology subject video many times so I given below the link of hematology playlist so you can touch and go on playlist on hematology 👇👇👇👇 • hematology Theory of rabies, Rabies lyssavirus, formerly Rabies virus (RABV), is a neurotropic virus that causes rabies in humans and animals. Rabies transmission can occur through the saliva of animals and less commonly through contact with human saliva. Rabies lyssavirus, like many rhabdoviruses, has an extremely wide host range. In the wild it has been found infecting many mammalian species, while in the laboratory it has been found that birds can be infected, as well as cell cultures from mammals, birds, reptiles and insects.[2] Rabies lyssavirus TEM micrograph with numerous rabies virions (small dark-grey rod-like particles) and Negri bodies (the larger pathognomonic cellular inclusions of rabies infection) TEM micrograph with numerous rabies virions (small dark-grey rod-like particles) and Negri bodies (the larger pathognomonic cellular inclusions of rabies infection) Virus classificatione (unranked): Virus Realm: Riboviria Kingdom: Orthornavirae Phylum: Negarnaviricota Class: Monjiviricetes Order: Mononegavirales Family: Rhabdoviridae Genus: Lyssavirus Species: Rabies lyssavirus Member viruses rabies virus Arctic rabies virus Synonyms[1] Rabies virus Rabies lyssavirus has a cylindrical morphology and is the type species of the Lyssavirus genus of the Rhabdoviridae family. These viruses are enveloped and have a single stranded RNA genome with negative-sense. The genetic information is packaged as a ribonucleoprotein complex in which RNA is tightly bound by the viral nucleoprotein. The RNA genome of the virus encodes five genes whose order is highly conserved. These genes code for nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G) and the viral RNA polymerase (L).[3] The complete genome sequences range from 11,615 to 11,966 nt in length.[4] All transcription and replication events take place in the cytoplasm inside a specialized “virus factory”, the Negri body (named after Adelchi Negri[5]). These are 2–10 µm in diameter and are typical for a rabies infection and thus have been used as definite histological proof of such infection.[6] #monututorialsacademy #microbiology #dmlt