Team mRNA | UMC Utrecht скачать в хорошем качестве

Team mRNA | UMC Utrecht

Metabolic diseases impact more than 10,000 families in the Netherlands. Since most metabolic disorders have no effective treatments, they are a leading cause of child death. TEAmRNA wants to change this. With cutting-edge technology, we’re getting to the core of these diseases: the genetic defect. With mRNA-nanomedicines we can temporarily restore these defects. Recently, we treated the first Dutch patients with mRNA-nanoparticles and results are encouraging! We are now developing an in-hospital production line for tailor-made mRNA-nanomedicines. Unfortunately, mRNA expression is short. Our patients require infusions every 2 weeks. Therefore we develop new mRNA-therapeutics that can achieve permanent correction of the disease-causing mutation with minimized risks. We have just treated the first animals in preparation for human patients. None of this would be possible without teamwork: translating cutting-edge genetic nanomedicine technologies from bench to patients into society in an ethically sound manner.