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Bowel cancer is the third most common cancer in both men and women. A substantial proportion of bowel cancer is preventable. The outlook depends strongly on how advanced it is at diagnosis; caught early the outlook is good, so screening is a major part of the public health response. Other cancers of the gut are changing incidence; stomach cancer rates are falling, while oesophageal cancer is increasing in men. This lecture will consider the prevention and treatment of these cancers. The transcript and downloadable versions of the lecture are available from the Gresham College website: https://www.gresham.ac.uk/lectures-an... Gresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham's mission, please consider making a donation: https://gresham.ac.uk/support/ Thumbnail Image © Annie Cavanagh CC BY-NC