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This video is about trigeminal neuralgia There are several causes that can lead to trigeminal neuralgia, a hyperactive dysfunction of the trigeminal nerve causing lancinating pain in the face which is often triggered by tactile stimulation. One of the causes is the trigeminal nerve vascular loop syndrome where a vascular loop compresses the trigeminal nerve at its root entry zone along the lateral pontine surface. Other causes might be inflammatory due to multiple sclerosis or compression due to a cisternal masses. In case of the vascular loop syndrome the best diagnostic clue is a high resolution T2 weigted MRI which shows a serpentine signal void in the cerebellopontine cisterne compressing the root of the trigeminal nerve with consecutive nerve atrophy. The offending vessel is the superior cerebellar artery in most of the times. It is important to notice though that it isn't uncommon to see a vessel in close contact to the trigeminal nerve but as long as there is no corresponding nerval atrophy or asymmetry to the contralateral nerve this condition is asymptomatic and without clinical relevance in most of the cases. Ofther findings that you might see in the clinical setting of a trigeminal neuralgia are bright lesions in the brainstem due to multiple sclerosis or a cisternal mass like an epidermoid, meningeoma or schwannoma leading to a nerve compression. Therapy is depending on the cause. Next to conservative drug therapy microvascular decompression is an option when having identified an offending vessel. Surgery yields a success rate of about 70%.