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This video is part 1 of a two part series of Lymph Node Pathology. Topics covered in this video are 1. Normal lymph node structure- components and IHC markers 2. Clinical and Pathological points to keep in mind when assessing a case of lymphadenopathy - especially a checklist for writing reports for PGs 3. Reactive changes in lymph nodes- three patterns 4. Some infectious lymphadenitis with examples Images explained in this video are 1. Normal lymph node structure (with animation) 2. Metastatic lymph node (2 slides) 3. Sinus histiocytosis 4. Follicular hyperplasia 5. Paracortical hyperplasia 6. Downey cells 7. CMV inclusions 8. HSV cytopathic effect on cells 9. Stellate granulomas of Cat Scratch disease 10. TB granuloma This video will prove useful to PGs in pathology to help them 1. Identify normal IHC, normal histology and examples of reactive and infectious lymphadenitis 2. Write theory answers on approach to lymphadenopathy 3. Prepare a checklist when examining lymph nodes under the microscope This video will also help MBBS graduates and PG exam aspirants with images and some previous year questions. References used in this video have been mentioned at places, and most of the theory has been referred to from one of the finest books on lymph node pathology- Ioachim's Lymph Node Pathology.