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🧬 Welcome to this complete MedicoMedics lecture on Syphilis — a high-yield overview for students and clinicians. Syphilis is a chronic sexually transmitted infection caused by Treponema pallidum, progressing through multiple stages and capable of serious systemic complications if left untreated. This lecture walks you through its pathophysiology, clinical manifestations, diagnosis, and treatment — with real-world relevance and exam focus. 🔍 Topics covered in this lecture: • What is Syphilis? Causes and bacterial features (Treponema pallidum) • Transmission modes (sexual, congenital) and evasion mechanisms • Clinical stages: • Primary (painless chancre) • Secondary (rash, lymphadenopathy, systemic symptoms) • Latent (asymptomatic) • Tertiary (neurosyphilis, cardiovascular involvement, gummas) • Congenital Syphilis features (Hutchinson teeth, saddle nose, rash) • Diagnosis: RPR, VDRL, FTA-ABS, dark-field microscopy • Treatment protocols: • Penicillin G as first-line (IM and IV depending on stage) • Alternatives for penicillin allergy • Management of Jarisch-Herxheimer reaction • Monitoring, follow-up, and HIV co-testing recommendations 📘 Perfect for: • Medical and nursing students preparing for infectious disease modules • Healthcare providers reviewing STI management • Board and exam preparation (high-yield format) 🔔 Subscribe to MedicoMedics for more clear, clinically relevant videos on microbiology, pathology, and physiology — updated weekly! 🛑 Disclaimer: This content is for educational purposes only. It is not a substitute for medical advice. #Syphilis #TreponemaPallidum #STIs #Neurosyphilis #MicrobiologyLecture #MedicalEducation #MedicoMedics #RPR #FTAABS #VDRL #Penicillin #InfectiousDiseases #medicomedics