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In the latest episode of Daily Value, we look at new research on creatine monohydrate's potential to enhance cognitive function, based on a recent meta-analysis published in Frontiers in Nutrition (PMID: 39070254). Traditionally used for its athletic performance benefits, creatine is now emerging as a promising supplement for brain health and cognitive enhancement. Talking Points: *Does creatine supplementation enhance cognitive function(s)? *Theoretical mechanisms: creatine enhances brain ATP levels through phosphocreatine resynthesis, offers neuroprotection against oxidative stress, and may act as a neuromodulator affecting neurotransmitters like acetylcholine. *Dosing strategies: The episode examines the complexities of optimal dosing protocols, discussing whether short-term high-dose loading or prolonged moderate dosing is more effective for increasing brain creatine concentrations. *Target populations: gender differences and health status may matter for who will experience more pronounced cognitive benefits from creatine supplementation. I discuss the practical implications of these findings and discuss whether creatine supplementation is right for you https://pubmed.ncbi.nlm.nih.gov/39070... https://www.sciencedirect.com/science...