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Roy van Wanrooij & Jeska Fritzsche on "Endoscopic ultrasound-guided choledochoduodenostomy using single-step lumen-apposing metal stents for primary drainage of malignant distal biliary obstruction (SCORPION-p): a prospective pilot study" Endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) using single-step lumen-apposing metal stents (LAMSs) was investigated as the primary drainage strategy in 22 consecutive patients with a distal biliary malignant obstruction without gastric outlet obstruction. In this prospective, single-center, pilot study, technical and clinical success rates of EUS-CDS were high (91% and 86 %, respectively), but the stent dysfunction rate (55%) was significant within 6 months’ follow-up, limiting the application of EUS-CDSwith LAMS as an alternative to endoscopic retrograde cholangiopancreatography. Find the article at: https://doi.org/10.1055/a-2134-3537 Jeska A. Fritzsche, Paul Fockens, Marc G. Besselink et al. Endoscopic ultrasound-guided choledochoduodenostomy using single-step lumen-apposing metal stents for primary drainage of malignant distal biliary obstruction (SCORPION-p): a prospective pilot study Endoscopy 2024; 56: 47–52 DOI 10.1055/a-2134-3537 ISSN 0013-726X © 2023. The Author(s). The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License