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New psychoactive substances (NPS), also called designer drugs or internet drugs, are newly created substances that often resemble existing illegal drugs. They do, however, have a chemical structure that hasn't been tested. Because of this, they are legal to sell and use, and some have serious side effects. So, why are they dangerous and how do forensic scientists combat them? In this video, you’ll hear about the history of one of these drugs, Cyclopropyl fentanyl, causing numerous deaths; what the researchers are doing about it and what electrophysiology is. In this video: Henrik Green, @LinkopingUniversity professor in Forensic Science and researcher at the Swedish National Board of Forensic Medicine; Dr. Nina Ottosson, staff scientist and electrophysiology expert at the SciLifeLab Chemical Biology Consortium Sweden (CBCS) unit. Who made the video? Niklas Norberg Wirtén, project lead, reporting, filming, editing; Hampus Pehrsson Ternström, project group, reporting; Victor Kuismin, project group. Follow us on LinkedIn for shorter updates on new exciting science: / science-for-life-laboratory What is SciLifeLab? In short: We are a national research infrastructure, funded by the Swedish government, that makes advanced instruments and expertise in molecular biosciences available to all researchers in Sweden (in short). Visit https://www.scilifelab.se/ to learn more.