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How many follicles are too many for an IUI? When should you move on to IVF? And is IUI ever a waste of time? In this episode, Dr. Sasha Hakman sits down with Dr. Blake Evans, a reproductive endocrinologist and researcher whose groundbreaking studies on ovarian stimulation and IUI have changed the way fertility specialists counsel patients every day. Dr. Evans breaks down his widely cited research on follicle count, multiples risk, and pregnancy rates across different age groups. He explains why singleton pregnancy rates stay the same whether you have one, two, three, or even five follicles, and why the only thing that increases with more follicles is the risk of multiples, especially in women under 38. We discuss the real risks of twin and triplet pregnancies, including preterm delivery, NICU stays, maternal complications, and the financial burden that can far exceed the cost of IVF itself. Dr. Evans also shares his second major study showing that patients can still conceive after multiple IUI cycles, with cumulative pregnancy rates reaching over 70% by cycle eight, though he emphasizes this does not mean it is the most efficient or cost effective path. This conversation is packed with practical takeaways for both patients and providers navigating unexplained infertility, insurance limitations, and the decision between continuing IUI or moving to IVF. Dr. Evans also shares candid insights on the Femeseed device, fresh transfers in IVF, and how geography and insurance coverage shape treatment decisions. If you are trying to decide how many IUI cycles to do, whether to cancel a cycle due to too many follicles, or if IVF is worth the investment, this episode will give you the data and clarity you need to move forward with confidence. _____ Follow Dr. Blake Evans on Instagram: @dr.blakeevans Follow me! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingtoconceivepod YouTube: @tryingtoconceivepod Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter to receive updates, answers to Q&A and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every 2 weeks. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!