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REMDESIVIR INJECTION, BASIC USE, PHARMAOLOGY, MECHANISMS, DOSE, CONTRAINDICATIONS, SIDE EFFECTS, Remdesivir Injection Remdesivir injection is used to treat coronavirus disease 2019 (COVID-19 infection) caused by the SARS-CoV-2 virus in hospitalized adults and children 12 years of age and older who weigh at least 88 pounds (40 kg). Remdesivir is in a class of medications called antivirals. It works by stopping the virus from spreading in the body. Remdesivir lyophilised powder for injection 100 mg), the only U.S. FDA approved Emergency Use Authorisation (EUA) treatment for patients with severe COVID-19 disease WHAT IS REMDESIVIR? Remdesivir is a broad-spectrum antiviral medication developed by the biopharmaceutical company Gilead Sciences As of 2020, remdesivir is being tested as a specific treatment for COVID-19, Authorized for emergency use in US & India REMDESIVIR INJECTION It is administered via injection into a vein It also received approval in the UK in May 2020 Antiviral activity against several RNA viruses including SARS coronavirus and MERS coronavirus, but it is not approved for any indication. Remdesivir was originally developed to treat hepatitis Mechanism of action REMDESIVIR As an adenosine nucleoside triphosphate analogue the active metabolite of remdesivir interferes with the action of viral RNA-dependent RNA polymerase Evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production Thus, inhibit the virus production SIDE EFFECTS REMDESIVIR The most common adverse effects in studies of remdesivir for COVID‑19 include Respiratory failure Organ impairment Including low albumin & low potassium Low count of red blood cells Low count of platelets that help with clotting Yellow discoloration of the skin #REMDESIVIR_INJECTION #ANTI_VIRAL_DRUGS #REMDESIVIR #COVID_10 #CORONA #EMERGENCY_DRUGS_FOR_CORONA #COVIFOR #CIPREMI #COVID_MEDICINE 👨🏼🏫 THIS EXPERT LECTURE BY 👨🏼🏫 MR AMAR M RAVAL ASSISTANT PROFESSOR FOUNDER PHARMAROCKS PHD SCOLAR (GTU AHMEDABAD) ☎️ CONTACT: 9016312020 📱 PHARMAROCKS E-LEARNING APP 📚 STUDY MATERIAL 👨🏼🏫 VIDEO LECTURE 📊 TEST SERIES 📱 ANDROID APP LINK https://play.google.com/store/apps/de... 📲 APPLE iPhone LINK https://apps.apple.com/in/app/my-inst... 📝 Org Code for iPhone = PHARMA ☎️ HELPLINE 9016312020 Follow us on YouTube: / pharmarocksthewayofsuccess Instagram: / pharmarocks Facebook: / pharmarocks77 Whatsapp helpline: 9016312020 Whatsapp group join: 9426180836 EMAIL ID: [email protected]