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This film from Johnson and Johnson shows the company's new surgical absorbable hemostat, known as Surgicel. Surgicel is a hemostatic agent (blood-clot-inducing material) made of an oxidized cellulose polymer (the unit is polyanhydroglucuronic acid), manufactured by the Ethicon subsidiary of Johnson And Johnson. It was introduced into clinical practice in 1947. It is used to control post-surgical bleeding. It is also used by some boxing cutmen to control bleeding. Surgicel is used extensively in oral and maxillofacial surgery to control intrabony arterial bleeds from the inferior alveolar artery. It is frequently used to stop bleeding following newborn circumcision if pressure alone is inadequate. When placed in the mandibular canal with the inferior alveolar nerve exposed there have been reports of neurotoxic effects. At the start of the film, research is shown with a dog used as a subject, whose liver is cut at 2:00. At 3:17 the liver of the dog is examined a couple of months later and no trace of the hemostat is visible. At 7:00, a dog's spleen is used for testing the uniformity of the product. The film also shows a liver biopsy and other surgeries in which the material can be extremely useful in promoting healing. At 14:06 the cellulose is used with a finger injury and its effects are quite pronounced, preventing delayed healing and hemorrhage. Oral surgery is seen at 14:48, with a patient having his lower teeth extracted. The film discusses the use of oxidized regenerated cellulose, a novel absorbable hemostatic material designed to control bleeding in difficult surgical situations. Despite advanced tools in modern operating rooms, hemorrhage remains a challenge, and this material has shown effectiveness in various animal models by quickly achieving hemostasis and being fully absorbed by the body without adverse tissue reactions. It has broad surgical applications, including cardiovascular, neurological, liver, oral, and emergency wound care, where it minimizes blood loss and promotes healing without causing irritation or secondary bleeding. Stability tests confirm its long shelf-life and maintained effectiveness, making it a valuable adjunct to traditional surgical techniques, especially in complex cases like hemophiliac patients or graft donor sites. While it does not replace meticulous surgical methods, oxidized regenerated cellulose significantly enhances bleeding control across many specialties. 0:00 — Instructions to focus and adjust volume/tone. 1:13 — Modern operating rooms have many tools but bleeding control remains challenging. 1:38 — Introduction of oxidized regenerated cellulose as a new material to control bleeding. 1:58 — Animal tests show rapid hemostasis in a dog liver wound using the material. 3:10 — Complete absorption of the material is observed after several weeks. 3:32 — Comparative tests in rats show minimal tissue reaction and full absorption within 15 days. 5:00 — Application in cardiovascular surgery reduces blood loss during graft implantation. 6:07 — Stability tests show material ages well with little loss of function. 7:24 — Aged material retains hemostatic effectiveness and absorbability. 7:47 — Explanation of how the material is made from purified cellulose with oxidation giving it unique properties. 9:57 — Use in human surgeries such as gallbladder and liver operations to control difficult bleeding. 11:52 — Comparison of traditional gauze vs. oxidized cellulose in skin graft donor sites shows better healing with cellulose. 13:33 — Use in emergency wounds like finger cuts prevents bleeding and aids healing without tissue adherence. 14:48 — Application in oral surgery after tooth extraction controls bleeding and promotes healing. 15:34 — Effective for hemophiliac patients to prevent both primary and secondary hemorrhage post-extraction. 17:04 — Cardiovascular surgery application in abdominal aortic aneurysm repair prevents blood loss. 17:40 — Neurological surgery application controls bleeding during brain tumor removal without causing irritation. 18:47 — Other surgical uses include sinus, thoracic, vascular, maxillofacial, abdominal, and orthopedic surgeries. 19:20 — Material is safe and effective but complements, not replaces, careful surgical technique. Motion picture films don't last forever; many have already been lost or destroyed. If you have endangered films you'd like to have scanned, or wish to donate celluloid to Periscope Film so that we can share them with the world, we'd love to hear from you. Contact us via the weblink below. This film is part of the Periscope Film LLC archive, one of the largest historic military, transportation, and aviation stock footage collections in the USA. Entirely film backed, this material is available for licensing in 24p HD, 2k and 4k. For more information visit http://www.PeriscopeFilm.com