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Elise Roth Tedeschi has been free of Stage IV Pancreatic Cancer since October 2012, but her journey was quite difficult, which she shares on this episode of the Cancer Interviews podcast. After noticing pain in her back, a CT scan revealed a 7cm tumor. She underwent a needle biopsy, then an endoscopic biopsy, after which a PET scan showed she had Stage IV Pancreatic Cancer. Elise had a port inserted, then underwent 12 rounds of folfirinox chemotherapy. Eventually a PET scan revealed there was no longer an active cancer in the tumor. She had one remaining procedure, and that was the removal of her gall bladder through a Nano-Knife procedure. Elise went into remission in October 2012, and while there are some things she cannot eat, Elise leads a productive life with her husband and two sons. An active career woman from Smyrna, Gerogia, Elise enjoyed normal health until until 2011 when she started to experience massive back pain and said her stomach felt like it was “on fire.” She sought medical attention, and tests showed she had a slightly bulging disc. A subsequent CT scan revealed Elise had a large, 7cm tumor in her pancreas. From a PET scan and a celiac plexis block, doctors told her she had Stage IV pancreatic cancer. The pain was so bad, she couldn’t eat. Elise told her husband of her diagnosis, then scheduled a conference call to inform her family. She later had to engage in a private conversation with her husband to discuss the possibility of her death and how it would affect her two teenage sons. She had a port inserted and underwent 12 rounds of folfirinox chemotherapy. In addition to the side effects associated with chemo, Elise’s dropped to 89 pounds. Elise was told for one diagnosed with Stage IV pancreatic cancer, the survival rate was like one percent, but was encouraged to learn that after six rounds of the chemotherapy, scans showed her tumor had shrunk in half. After the twelfth round, the tumor was still there, but it had shrunk some more. Then in October, 2012, another PET scan was run and Elise Roth Tedeschi was told that while the tumor, it was no longer active. Doctors decided against a Whipple procedure, but proceeded with what was a state-of-the-art procedure called Nano-Knife. Her gall bladder was removed, and the procedure shocks the cells in what was left of her tumor. She then had her port removed, and continued with a pill form of chemotherapy. That, and the Nano-Knife completely dissolved Elise’s tumor. Elise still gets scans every six months, but has defied the odds, being in remission since October 2012. She says she has had to make minor challenges, but her day-to-day life is very close to what it was prior to her diagnosis. Additional Resources: Pancreatic Cancer Action Network: https://www.pancan.org