Introduction to RANKL | RANK | OPG Signaling Pathway скачать в хорошем качестве

Introduction to RANKL | RANK | OPG Signaling Pathway

Lesson on the RANKL / RANK / OPG Signaling Pathway: Purpose and Mechanism. The RANKL-RANK-OPG Signaling pathway is an important pathway in bone remodelling and is important in various osteopathies such as osteoporosis. Osteoblasts are bone forming cells, which express and release the protein RANK ligand (RANKL) and osteoprotegerin (OPG). RANK ligand binds to the RANK receptor, which is located on bone absorbing cells known as osteoclasts. RANK ligand binding to RANK receptor leads to the differentiation and activation of osteoclasts. Activation of osteoclasts enables them to reabsorb bone to ensure bone remodelling occurs. Hey everyone. In this lesson you will learn about the RANKL-RANK-OPG Signaling Pathway, its purpose in bone remodelling, and the various downstream signaling targets of the pathway, including PI3K-AKT signaling, JNK signaling, and NFKB signaling. I hope you find this video helpful. If you do, please like and subscribe to keep up-to-date on my newest videos. JJ Subscribe for more free medical lessons    / @jjmedicine   ------------------------------------------------------------------------------------------------------------- For books and more information on these topics https://www.amazon.com/shop/jjmedicine Support future lessons (and get other cool stuff) ➜   / jjmedicine   Follow me on Twitter! ➜   / jj_medicine   Come join me on Facebook! ➜   / jj-medicine-100642648161192   Start your own website with BlueHost ➜ https://www.bluehost.com/track/jjmedi... Check out the best tool to help grow your YouTube channel (it’s helped me!) https://www.tubebuddy.com/jjmedicine ------------------------------------------------------------------------------------------------------------- Check out some of my other lessons. Medical Terminology - The Basics - Lesson 1:    • Medical Terminology - The Basics - Lesson 1   Fatty Acid Synthesis Pathway:    • Fatty Acid Synthesis Pathway: Overview, En...   Wnt/B Catenin Signaling Pathway:    • Wnt/β-Catenin Signaling Pathway | Overview...   Upper vs. Lower Motor Neuron Lesions:    • Upper and Lower Motor Neuron Lesions | UMN...   Lesson on the Purine Synthesis and Salvage Pathway:    • Purine Synthesis and Salvage Pathway   Gastrulation | Formation of Germ Layers:    • Gastrulation | Formation of Germ Layers | ...   Introductory lesson on Autophagy (Macroautophagy):    • Autophagy | Macroautophagy & Importance in...   Infectious Disease Playlist    • Infectious Diseases   Dermatology Playlist    • Dermatology   Pharmacology Playlist    • Pharmacology   Hematology Playlist    • Hematology   Rheumatology Playlist    • Rheumatology   Endocrinology Playlist    • Endocrinology   Nephrology Playlist    • Nephrology   ---------------------------------------------------------------------------------------------------- **MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition. ---------------------------------------------------------------------------------------------------- Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know. I am always looking for ways to improve my lessons! Please don't hesitate to leave me feedback and comments - all of your feedback is greatly appreciated! :) And please don't hesitate to send me any messages if you need any help - I will try my best to be here to help you guys :) Thanks for watching! If you found this video helpful, please like and subscribe! JJ