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This comprehensive educational resource delves into the critical subject of End Stage Renal Disease (ESRD), often referred to as end-stage kidney disease. Designed to serve both healthcare professionals and patients, the tutorial unpacks what is end stage renal disease, its pathophysiology, and its intersection with chronic kidney disease. The presentation provides an in-depth understanding of end stage renal disease symptoms, highlighting how they differ from or are an extension of symptoms of general kidney disease. It also discusses the causes of end stage renal disease, shedding light on the various risk factors and underlying medical conditions that can lead to this severe form of renal disease. For healthcare providers, particularly in the field of nursing, the end stage renal disease nursing segment offers valuable insights into the management and care strategies, emphasizing the unique needs and challenges of treating patients with ESRD. The tutorial also introduces the end stage renal disease program, detailing the various treatment options and supportive care available for managing the condition. It includes conventional medical approaches as well as a segment on end stage renal disease ayurvedic treatment, for those interested in alternative therapies. In a bid to make this resource accessible to a wider audience, there is a segment on end stage renal disease in Hindi, led by Dr. Sumanta, focusing on the key aspects of diagnosis, symptoms, and management strategies tailored to the specific needs of Hindi-speaking populations. Overall, this resource aims to be a comprehensive guide on ESRD, encapsulating topics from diagnosis to treatment, and is designed to cater to a diverse audience interested in understanding this complex form of renal disease.