MHC (Major Histocompatibility Complex)| Self vs Non-Self Recognition скачать в хорошем качестве

MHC (Major Histocompatibility Complex)| Self vs Non-Self Recognition

In this lecture, we explain Major Histocompatibility Complex (MHC) Class II in a clear, conceptual, and exam-oriented manner. This topic is extremely important for UPPSC Assistant Professor Zoology, CSIR-NET, DBT, B.Sc / M.Sc, and all Immunology competitive exams. MHC & Self vs Non-Self Recognition [00:01] Introduction and Overview: Introduction to the immunology series focusing on the UPHESC Assistant Professor Zoology syllabus. [00:33] Role of MHC: Explanation of how Major Histocompatibility Complex (MHC) molecules facilitate the differentiation between self-cells and foreign microbes. [01:44] MHC Function: Description of MHC molecules binding to peptide fragments derived from pathogens and displaying them on the cell surface. [03:49] MHC Class I vs Class II: Comparison of MHC Class I (found on all nucleated cells) and MHC Class II (found on professional Antigen Presenting Cells like macrophages and B cells). [08:37] Genetic Basis of MHC: Definition of MHC as a tightly linked cluster of genes in vertebrates that determines tissue transplant compatibility. [13:11] MHC Location (HLA vs H2): Mapping of MHC on Human Chromosome 6 (HLA) and Mouse Chromosome 17 (H2). [15:58] Key MHC Properties: Discussion on the Polygenic and Polymorphic nature of MHC, which makes it difficult for pathogens to evade the immune system. [20:30] Classification of MHC Genes: Breakdown of Class I, Class II, and Class III MHC genes and their specific roles in presenting antigens to T cells. [25:23] Non-Classical MHC Genes: Explanation of genes that do not function in the presentation of peptide antigens to T cells. [26:36] Structural Comparison: Detailed analysis of the molecular structure of MHC Class I and Class II, including peptide-binding domains and subunits. [32:38] Transmembrane Regions: Comparison of transmembrane domains between the two classes, highlighting the Beta-2 microglobulin unit in Class I. [34:23] Human HLA Complex Map: Visual representation and explanation of the structural gene arrangement of the Human HLA complex. YouTube Growth Strategy Analysis: SEO: The video effectively targets high-competition academic keywords like #immunology, #csirnet, and #uppsc. Engagement: The content is structured specifically for exam aspirants (UPHESC), ensuring high retention from a niche audience. Structure: Using clear diagrams and side-by-side comparisons (Class I vs II) enhances visual learning and watch time.    •  MHC (Major Histocompatibility Complex)| S...   🔬 What you will learn in this video: • What is MHC (Major Histocompatibility Complex) • Structure and function of MHC Class II molecules • Self vs Non-Self recognition mechanism • Role of Antigen Presenting Cells (APCs) • Interaction of MHC Class II with CD4⁺ T helper cells • Immunological significance & exam-oriented points • Frequently asked MCQs & conceptual traps 📌 This lecture is designed to help students build concepts from basics to advanced level, exactly as required for Assistant Professor, NET, DBT, and University exams. 🎯 Useful for: ✔ UPPSC Assistant Professor Zoology ✔ CSIR-NET Life Sciences ✔ DBT JRF ✔ B.Sc / M.Sc Zoology & Life Science ✔ Competitive Immunology Exams 📚 Subscribe for more high-quality Zoology & Immunology lectures 🔔 Don’t forget to LIKE, SHARE & COMMENT for doubt discussion #MHC #MHCClass2 #MajorHistocompatibilityComplex #Immunology #SelfVsNonSelf #AntigenPresentation #APC #CD4TCells #HelperTCells #ImmunologyConcepts #Zoology #ZoologyLectures #UPPSC #UPPSCAssistantProfessor #AssistantProfessorZoology #CSIRNET #CSIRNETLifeScience #DBT #DBTJRF #LifeScience #Biology #ImmunologyLecture #CompetitiveExams #ExamOriented #MCQBasedLearning #ConceptBasedLearning #BScZoology #MScZoology #UniversityExams #PGEntrance #NETPreparation #TeachingExams #HigherEducation #ImmunologyForNET #ImmunologyForUPPSC #ZoologyTeacher #OnlineLearning #ConceptClarity #ScienceEducation #IndianExams #AcademicBiology #ImmunologyNotes #ZoologyNotes #BiologyStudents #LifeScienceStudents #ImmunologySimplified #CellMediatedImmunity #AdaptiveImmunity #AntigenProcessing #TCellActivation #ProfessionalTeaching #UPSCZoology #StatePSC #LecturerExam #AssistantProfessorExam #ZoologyOptional #BiologyPreparation #StudyWithMe #DailyBiology #ExamReady #QualityEducation #AcademiaBiology #IndianTeachers #ScienceCommunity #LearningBiology #ImmunologyBasics #AdvancedImmunology #ZoologyCommunity #NETJRF #ResearchAspirants #FutureProfessor #TeachingCareer #BiologyConcepts #ZoologyEducation #ImmunologyClass