POLIETILENGLICOL 4000, PEG 4000, polyethylene glycol 4000 review EN ESPAÑOL скачать в хорошем качестве

POLIETILENGLICOL 4000, PEG 4000, polyethylene glycol 4000 review EN ESPAÑOL

What is Polyethylene Glycol 4000? Polyethylene Glycol 4000, also known as Macrogol 4000, is a high-molecular-weight synthetic polymer. It belongs to a class of medications called osmotic laxatives. It is commonly available as a powder or granule to dissolve in water and is administered orally. What is it used for? Polyethylene Glycol 4000 is indicated for the treatment of occasional constipation in adults and children. Its main function is to facilitate and regulate bowel movements. It acts physically and is not absorbed by the body, making it an effective treatment with a good safety profile for restoring normal bowel movements. How to take it? Polyethylene Glycol 4000 should be administered following the doctor's instructions or the instructions in the package insert. The dosage may vary depending on age and individual needs. Preparation and dosage for adults and adolescents over 12 years of age: The usual dose is 1 sachet per day, dissolved in approximately 150 ml of water. Shake well until the powder is completely dissolved and then drink immediately. Dosage for children: For children 8 years of age and older, the dose may be half a sachet to one sachet per day, as recommended by a doctor. For children under 8 years of age, a doctor should determine the dosage and suitability of the treatment. Time of administration: It can be taken at any time of day, with or without food. For convenience, many people prefer to take it in the morning. Hydration: It is important to drink plenty of fluids throughout the day while taking this medication, as this enhances its effect. Improvement is usually noticed after 24 to 48 hours of administration. It is not intended for prolonged use without medical supervision. If constipation persists after several days of treatment, consult a doctor. Properties. The main property of Polyethylene Glycol 4000 is its physical osmotic action in the intestine. Mechanism of action: Once ingested and dissolved in water, the Polyethylene Glycol 4000 solution increases osmolarity in the intestinal lumen. This means it attracts and retains water from the body into the intestine, hydrating and softening the stool evenly. Increased volume: By softening the stool and increasing its water content, it also increases its volume. This additional volume gently stimulates the natural movement of intestinal peristalsis, facilitating evacuation. Nonabsorbable: It is a large molecule that is not absorbed in the gastrointestinal tract, is not metabolized, and does not pass into the bloodstream. It is completely eliminated in the stool. Benefits The main benefits of Polyethylene Glycol 4000 are: High efficacy: Provides effective and predictable relief from constipation. Gentle and physiological action: It does not cause urgency or painful abdominal cramps, unlike some stimulant laxatives. Safety: Since it is not absorbed by the body, it has a favorable safety profile and is suitable for use in children and adults. Non-habit forming: Unlike other laxatives, its physical mechanism of action does not cause habituation or "lazy bowel" when used correctly. Neutral taste: It is generally tasteless or has a very mild taste, making it easy to swallow. Side effects: Polyethylene glycol 4000 is generally well tolerated. Side effects, if they occur, are usually mild and transient. Very rare: In some cases, mild abdominal discomfort, bloating, excessive flatulence, gas, or nausea may occur. These sensations usually disappear within a few days of continued use or with a dose adjustment. Allergic reactions: These are very rare, but skin rashes, itching, or hives have been reported in isolated cases. If severe diarrhea, severe or persistent abdominal pain, or any signs of an allergic reaction occur, treatment should be discontinued and a doctor consulted. Contraindications: The use of Polyethylene Glycol 4000 is contraindicated in the following situations: Patients with a known hypersensitivity to Polyethylene Glycol Macrogol or any of the components of the preparation. Patients with serious medical conditions affecting the gastrointestinal tract, such as intestinal obstruction, gastric or intestinal perforation, or paralytic ileus or absence of bowel movement. In cases of abdominal pain of unknown origin, nausea, vomiting, or fever, do not use without prior medical evaluation. Do not administer if appendicitis or severe intestinal inflammation such as Crohn's disease is suspected.