Biliary-driven Liver Regeneration Study by Hepatocyte Ablation | Protocol Preview скачать в хорошем качестве

Biliary-driven Liver Regeneration Study by Hepatocyte Ablation | Protocol Preview

Watch the Full Video at https://www.jove.com/v/52785/hepatocy.... Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration - a 2 minute Preview of the Experimental Protocol Tae-Young Choi, Mehwish Khaliq, Sungjin Ko, Juhoon So, Donghun Shin University of Pittsburgh, Department of Developmental Biology, McGowan Institute for Regenerative Medicine; To help assess the molecular mechanisms underlying zebrafish biliary-driven liver regeneration, we established a liver injury model in which the nitroreductase-expressing hepatocytes are genetically ablated upon metronidazole treatment. In this protocol, we describe how to adeptly manipulate, monitor and analyze hepatocyte ablation and biliary-driven liver regeneration. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments